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A cardiologist warns: these 5 medications increase the risk of heart attack and stroke in older people

Posted on July 17, 2026 by Admin

Medications and Heart Risk in Older Adults: What to Know

Headlines claiming that certain medicines “cause heart attacks and strokes” can be misleading. Many medications that have potential risks are also life-saving when prescribed appropriately. The risk often depends on the person’s age, health conditions, dose, other medicines, and how the medication is used.

Some medication groups that may require extra caution in older adults include:

1. Certain NSAID pain relievers

Examples:

  • Ibuprofen
  • Naproxen

These medicines can increase blood pressure and may raise the risk of heart-related problems in some people, especially with long-term use or high doses.

2. Some decongestants

Examples:

  • Pseudoephedrine (found in some cold and allergy medicines)

These can raise blood pressure and heart rate, which may be a concern for people with hypertension or heart disease.

3. Certain diabetes medications (in specific situations)

Some diabetes medicines require careful selection based on a person’s heart and kidney health. Doctors consider the overall risk-benefit balance when prescribing them.

4. Some hormone-based medications

Certain hormone therapies may increase the risk of blood clots or cardiovascular events in some people, depending on factors such as age, timing, and health history.

5. Some stimulant medications

Certain prescription stimulants can increase heart rate and blood pressure and may require monitoring in people with cardiovascular disease.


Medicines that are often misunderstood

Some medications that appear on “warning” lists are actually used to reduce heart attack and stroke risk, such as:

  • Blood pressure medications
  • Statins for cholesterol
  • Antiplatelet medicines when prescribed

The key is using the right medication for the right person.

Older adults should:

  • Review all medicines and supplements regularly with a healthcare professional or pharmacist.
  • Avoid starting over-the-counter medications without checking for interactions.
  • Monitor blood pressure and other relevant health measurements.

If you share the names of the medications you’re concerned about, I can explain their known heart-related risks and why they may or may not be appropriate.

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